Phospho-VASP-S157 Monoclonal Antibody (CABP1511)
- SKU:
- CABP1511
Description
| Product Name: | Phospho-VASP-S157 Monoclonal Antibody |
| Product Code: | CABP1511 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC64201 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HEL, HEL+Forskolin |
| Cellular Location: | Cytoplasm, cytoskeleton |
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
| Immunogen: | A synthetic phosphorylated peptide around S157 of human VASP(NP_003361.1). |
| Sequence: | EHIER RVS(p )NAGG P-C |
| Synonyms: | VASP |
| Calculated MW: | 40kDa |
| Observed MW: | 50kDa |
Additional Information
Product Type: |
Antibody |
Antibody Type: |
Monoclonal Antibody |
Reactivity: |
Human |
Host Species: |
Rabbit |
Isotype: |
IgG |
Applications: |
WB |
Related Products
Phospho-VASP-S157 Monoclonal Antibody (CABP1510)
Phospho-Tau-S404 Monoclonal Antibody
