Phospho-PKC zeta-T410 Polyclonal Antibody
_WB_01__39721__26504.1706546659.jpg?c=1 "Phospho-PKC zeta-T410 Polyclonal Antibody")
- SKU:
- CABP0433
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
_WB_01__39721__26504.1706546659.jpg?c=1&imbypass=on "Phospho-PKC zeta-T410 Polyclonal Antibody")
Description
| Product Name: | Phospho-PKC zeta-T410 Polyclonal Antibody |
| Product Code: | CABP0433 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | 293F |
| Cellular Location: | Cell junction, Cytoplasm, Endosome |
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Immunogen: | A phospho specific peptide corresponding to residues surrounding T410 of human PKC (pan) (zeta). |
| Sequence: | Email for sequence |
| Synonyms: | PKC2, PKC-ZETA |
| Calculated MW: | 68kDa |
| Observed MW: | 85kDa |
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