Description
Product Name: | Phospho-GSK3α-S21+GSK3β-S9 Monoclonal Antibody |
Product Code: | CABP1341 |
Reactivity: | Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC54771 |
Reactivity: | Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | NIH/3T3+FBS |
Cellular Location: | Cell membrane, Cytoplasm, Nucleus |
Customer Validation: | WB(Mus musculus,Homo sapiens) |
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen: | A synthetic phosphorylated peptide around S21&S9 of human GSK3α/GSK3β (NP_063937.2/NP_002084.2). |
Sequence: | TSSFA |
Synonyms: | GSK3B, GSK 3 beta, GSK3A, GSK 3 alpha |
Calculated MW: | 51kDa/46kDa |
Observed MW: | 51kDa/46kDa |