Phospho-c-Jun (Ser73) In-Cell ELISA

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SKU:
CBCAB01510
Product Type:
ELISA Kit
ELISA Type:
Cell Based Phospho Specific
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Detection Method:
Colorimetric

Description

Technical Manual

Phospho-c-Jun (Ser73) Cell-Based ELISA

Product Description:The Phospho-c-Jun (Ser73) Colorimetric Cell-Based ELISA Kit allows for qualitative detection of Phospho-c-Jun(Ser73) in plated and fixed cells.
Target Synonyms:Activator protein 1; AH119; AP-1; AP1; c-Jun; Jun A; p39; Proto-oncogene c-jun; RJG-9; V-jun avian sarcoma virus 17 oncogene homolog
Detection Target:Phospho-IRAK1(Thr209)
Reactivity:H:S73, M:S73, R:S73
Pack Size:2 x 96 assays
Detection Method:Colorimetric 450 nm
Format:Cell-Based ELISA/In-Cell ELISA
Storage and Stability Guarantee:4 °C/6 Months
Sample Type:Plated & fixed cells
Range:5000 cells/well minimum
Time:4.5 hours

Phospho-c-Jun (Ser73) Cell-Based ELISA Protein Information

UniProt Protein Function:Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
NCBI Summary:This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]
UniProt Code:P05412
NCBI GenInfo Identifier:135298
NCBI Gene ID:3725
NCBI Accession:P05412.2
UniProt Secondary Accession:P05412,Q6FHM7, Q96G93,
UniProt Related Accession:P05412
Molecular Weight:
NCBI Full Name:Transcription factor AP-1
NCBI Synonym Full Names:jun proto-oncogene
NCBI Official Symbol:JUN
NCBI Official Synonym Symbols:AP1; AP-1; c-Jun
NCBI Protein Information:transcription factor AP-1
UniProt Protein Name:Transcription factor AP-1
UniProt Synonym Protein Names:Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39
Protein Family:C-Jun-amino-terminal kinase-interacting protein
UniProt Gene Name:JUN
UniProt Entry Name:JUN_HUMAN
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