Phospho-AMPKa1-T183 + AMPKa2-T172 Monoclonal Antibody
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- SKU:
- CABP1345
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Phospho-AMPKa1-T183 + AMPKa2-T172 Monoclonal Antibody |
| Product Code: | CABP1345 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC53386 |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | C2C12+oligomycin |
| Cellular Location: | Apical plasma membrane, Cytoplasm, Cytosol, Nuclear speck, Nucleoplasm, nucleus |
| Customer Validation: | WB(Gallus gallus) |
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
| Immunogen: | A synthetic phosphorylated peptide around T183 of human AMPKa1 (NP_006242.5). |
| Sequence: | LRTSC |
| Synonyms: | AMPKa1/AMPKa2 |
| Calculated MW: | 64kDa/65kDa/62kDa |
| Observed MW: | 62kDa |
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