Description
Product Name: | PFKP Polyclonal Antibody |
Product Code: | CAB21538 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Cellular Location: | Cytoplasm |
This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 605-784 of human PFKP (NP_002618.1). |
Sequence: | IFEEP FDIRD LQSNV EHLTE KMKTT IQRGL VLRNE SCSEN YTTDF IYQLY SEEGK GVFDC RKNVL GHMQQ GGAPS PFDRN FGTKI SARAM EWITA KLKEA RGRGK KFTTD DSICV LGISK RNVIF QPVAE LKKQT DFEHR IPKEQ WWLKL RPLMK ILAKY KASYD VSDSG QLEHV QPWSV |
Synonyms: | PFKF, PFK-C, PFK-P, ATP-PFK |
Calculated MW: | 86kDa |
Observed MW: | Refer to figures |