Description
Product Name: | PerCP/Cyanine5.5 Anti-Human CD48 Antibody [156-4H9] |
Product Code: | AGEL2831 |
Clone No: | 156-4H9 |
Synonyms: | CD48 antigen,Cd48,BCM1 surface antigen,BLAST-1,HM48-1,MRC OX-45 surface antigen,SLAMF2,sgp-60,CD48 |
Reactivity: | Human |
Host Species: | Mouse |
Applications: | FCM |
Isotype: | Mouse IgG1, κ |
Isotype Control: | PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL2555) |
Conjugation: | PerCP/Cyanine5.5 |
Form: | Liquid |
Fluorescent Label: | PerCP/Cyanine5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter). |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Swissprot: | P09326 |
Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Shipping: | Biological ice pack at 4°C |
CD48 is a 40-47 kD GPI-anchored membrane protein, also known as Blast-1 and HuLy-m3. It is a member of the CD2 family that contains 2 IgSF domains and is widely expressed on both resting and activated hematopoietic cells with the exception of granulocytes, platelets, and erythrocytes. CD48 binds to CD2 at a considerably (>100-fold) lower affinity than CD58. It is thought to contribute to T cell activation. The cytoplasmic tail of CD48 has been shown to bind to the kinases Lck and Fyn.