PE/GenieFluor 594 Anti-Mouse CD86 Antibody [GL-1] (AGEL3175)

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SKU:
AGEL3175
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
GL-1
Conjugation:
PE/AF594

Description

Product Name:PE/AF594 Anti-Mouse CD86 Antibody [GL-1]
Product Code:AGEL3175
Size:50 Tests, 100 Tests, 200 Tests
Clone No:GL-1
Synonyms:T-lymphocyte activation antigen CD86, Cd86, Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1
Reactivity:Mouse
Host Species:Rat
Applications:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/GenieFluor 594 Rat IgG2a, κ Isotype Control [2A3] (AGEL3469)
Conjugation:PE/AF594
Applications:FCM
Recommended Dilution:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Fluorescent Label:PE/GenieFluor 594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter).
Shipping:Biological ice pack at 4°C
Form:Liquid
Gene ID:12524
Swissprot:P42082
Background Information:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
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