PE/GenieFluor 594 Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL3187)

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SKU:
AGEL3187
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
FGK4.5/FGK45
Conjugation:
PE/AF594

Description

Product Name:PE/AF594 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
Product Code:AGEL3187
Size:50 Tests, 100 Tests, 200 Tests
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5, Cd40, B-cell surface antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5
Reactivity:Mouse
Host Species:Rat
Applications:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/GenieFluor 594 Rat IgG2a, κ Isotype Control [2A3] (AGEL3469)
Conjugation:PE/AF594
Applications:FCM
Recommended Dilution:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Fluorescent Label:PE/GenieFluor 594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter).
Shipping:Biological ice pack at 4°C
Form:Liquid
Gene ID:21939
Swissprot:P27512
Background Information:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
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