PE/GenieFluor 594 Anti-Mouse CD106 Antibody [M/K-2.7] (AGEL3239)
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- SKU:
- AGEL3239
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- Rat IgG1, k
- Clone:
- M/K-2.7
- Conjugation:
- PE/AF594
Description
| Product Name: | PE/AF594 Anti-Mouse CD106 Antibody [M/K-2.7] |
| Product Code: | AGEL3239 |
| Size: | 25ug, 100ug |
| Clone No: | M/K-2.7 |
| Synonyms: | Vascular cell adhesion protein 1, Vcam1, V-CAM 1, VCAM-1, CD106 |
| Reactivity: | Mouse |
| Host Species: | Rat |
| Applications: | FCM |
| Isotype: | Rat IgG1, κ |
| Isotype Control: | PE/GenieFluor 594 Rat IgG1, κ Isotype Control [HRPN] (AGEL3468) |
| Conjugation: | PE/AF594 |
| Applications: | FCM |
| Recommended Dilution: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume]. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Fluorescent Label: | PE/GenieFluor 594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter). |
| Shipping: | Biological ice pack at 4°C |
| Form: | Liquid |
| Gene ID: | 22329 |
| Swissprot: | P29533 |
| Background Information: | CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin). |
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