Description
Product Name: | PE/AF594 Anti-Human CD58 Antibody [TS2/9.1] |
Product Code: | AGEL3223 |
Size: | 20 Tests, 100 Tests, 200 Tests |
Clone No: | TS2/9.1 |
Synonyms: | Lymphocyte function-associated antigen 3, CD58, Ag3, Surface glycoprotein LFA-3, LFA3 |
Reactivity: | Human |
Host Species: | Mouse |
Applications: | FCM |
Isotype: | Mouse IgG1, κ |
Isotype Control: | PE/GenieFluor 594 Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL3461) |
Conjugation: | PE/AF594 |
Applications: | FCM |
Recommended Dilution: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Fluorescent Label: | PE/GenieFluor 594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter). |
Shipping: | Biological ice pack at 4°C |
Form: | Liquid |
Gene ID: | 965 |
Swissprot: | P19256 |
Background Information: | CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface. |