PE/Cyanine5 Anti-Human CD28 Antibody [CD28.2]
- SKU:
- AGEL2370
Description
| Product Name: | PE/Cyanine5 Anti-Human CD28 Antibody [CD28.2] |
| Product Code: | AGEL2370 |
| Clone No: | CD28.2 |
| Synonyms: | PAS2,MNS,HGpMiX,GYPA,GPSAT |
| Reactivity: | Human |
| Host Species: | Mouse |
| Applications: | FCM |
| Isotype: | Mouse IgG1, κ |
| Conjugation: | PE/Cyanine5 |
| Form: | Liquid |
| Fluorescent Label: | PE/Cyanine5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 670 nm (e.g., a 690/50 nm bandpass filter). |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Swissprot: | P10747 |
| Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
Additional Information
Product Type: |
Antibody |
Antibody Type: |
Monoclonal Antibody |
Applications: |
FCM |
Reactivity: |
Human |
Host Species: |
Mouse |
Isotype: |
Mouse IgG1, κ |
Clone: |
CD28.2 |
Conjugation: |
PE/Cyanine5 |
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