PDX-1 Monoclonal Antibody (CPAB0733)
- SKU:
- CPAB0733
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Applications:
- WB
- Applications:
- IHC
Description
system_update_alt Datasheet
| Product Name: | PDX-1 antibody |
| Product Sku: | CPAB0733 |
| Size: | 10μl |
| Host Species: | |
| Immunogen: | Recombinant PDX1 E.Coli derived. |
| Clone: | |
| Reactivity: | Other Polyclonal bodies |
| Applications: | Western Blot, Immunohistochemistry |
| Purification Method: | |
| Isotype: | |
| Background: | PDX1 activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. IPF1 is particularly involved in glucose-dependent regulation of insulin gene transcription. Pancreas Duodenum Homeobox-1 binds preferentially the DNA motif 5'-[ct]taat[tg]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, it is required for maintaining the hormone-producing phenotype of the beta-cell. |
| Synonyms: | IPF1, IUF1, IDX-1, MODY4, PDX1, STF-1, Insulin promoter factor 1, Pancreas Duodenum Homeobox-1. |
| Storage Buffer: |
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