PDK1/PDPK1 Polyclonal Antibody
- SKU:
- CAB21810
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | PDK1/PDPK1 Polyclonal Antibody |
| Product Code: | CAB21810 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:6000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, A-549, HCT116, Rat lung |
| Cellular Location: | Cell junction, Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein, focal adhesion |
Enables 3-phosphoinositide-dependent protein kinase activity; phospholipase activator activity; and phospholipase binding activity. Involved in several processes, including cell surface receptor signaling pathway; regulation of protein kinase activity; and regulation of signal transduction. Acts upstream of or within intracellular signal transduction. Located in cell projection; cytosol; and plasma membrane. Implicated in prostate cancer. Biomarker of lung non-small cell carcinoma.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 409-556 of human PDK1/PDPK1 (NP_002604.1). |
| Sequence: | GSNIE QYIHD LDSNS FELDL QFSED EKRLL LEKQA GGNPW HQFVE NNLIL KMGPV DKRKG LFARR RQLLL TEGPH LYYVD PVNKV LKGEI PWSQE LRPEA KNFKT FFVHT PNRTY YLMDP SGNAH KWCRK IQEVW RQRYQ SHPDA AVQ |
| Synonyms: | PDK1, PDPK2, PDPK2P, PRO0461 |
| Calculated MW: | 63kDa |
| Observed MW: | 58-68kDa |
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