pan-Trk Polyclonal Antibody
- SKU:
- CAB22121
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | pan-Trk Polyclonal Antibody |
| Product Code: | CAB22121 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse brain |
| Cellular Location: | axon, dendrite, early endosome, late endosome, plasma membrane |
Neurotrophic tyrosine kinase (NTRK) is a family of receptor tyrosine kinase.The NTRK gene family contains three members, NTRK1, NTRK2 and NTRK3, which produce TRKA, TRKB and TRKC proteins, respectively.TRK kinases leads to cell differentiation and may play important roles in normal neural functions.Rearrangements in the NTRK genes can result in two genes fusing together and producing altered TRK proteins, which can lead to uncontrolled growth of cancer cells. Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are an actionable biomarker for cancer therapy and can be found in over 25 different types of cancer.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 697-796 of human pan-Trk (NP_002520.2). |
| Sequence: | ESILY RKFTT ESDVW SFGVV LWEIF TYGKQ PWYQL SNTEA IDCIT QGREL ERPRA CPPEV YAIMR GCWQR EPQQR HSIKD VHARL QALAQ APPVY LDVLG |
| Observed MW: | 120-140kDa |
Related Products
pan-Trk Monoclonal Antibody
OverviewProduct Name:pan-Trk Monoclonal AntibodyProduct Code:CAB23241Reactivity:Human, Mouse, RatApplications:Western blotting
TRK fused gene (TFG) Polyclonal Antibody
OverviewProduct Name:TRK fused gene (TFG) Polyclonal AntibodyProduct Code:CAB21329Reactivity:HumanApplications:Western blotting</
Pan Phospho-T Polyclonal Antibody
OverviewProduct Name:Pan Phospho-T Polyclonal AntibodyProduct Code:CABP1513Reactivity:Human, MouseApplications:Western blotting</
pan 14-3-3 Polyclonal Antibody
OverviewProduct Name:pan 14-3-3 Polyclonal AntibodyProduct Code:CAB23674Reactivity:Human, Mouse, Rat, African green monkeyApplications:
Doublecortin Polyclonal Antibody
OverviewProduct Name:Doublecortin Polyclonal AntibodyProduct Code:CAB0149Reactivity:Human, MouseApplications:Western blotting, Im