PADI3 Polyclonal Antibody
- SKU:
- CAB10652
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | PADI3 Polyclonal Antibody |
| Product Code: | CAB10652 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm |
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PADI3 (NP_057317.2). |
| Sequence: | MSLQR IVRVS LEHPT SAVCV AGVET LVDIY GSVPE GTEMF EVYGT PGVDI YISPN MERGR ERADT RRWRF DATLE IIVVM NSPSN DLNDS HVQIS YHSSH EPLPL AYAVL YLTCV DISLD CDLNC EGRQD RNFVD KRQWV WGPSG YGGIL LVNCD RDDPS CDVQD NCDQH VHCLQ DLEDM SVMVL RTQGP AALFD DHKLV LHTSS YDAKR AQVFH ICGPE DVCEA YRHVL GQDKV SYEVP RLHGD EERFF VEGLS FPDAG FTGLI SFHVT LLDDS NEDFS |
| Synonyms: | PAD3, PDI3, UHS1 |
| Calculated MW: | 75kDa |
| Observed MW: | Refer to figures |
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