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Description
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NUDT5 Recombinant Protein
ADP-sugar Pyrophosphatase, also known as NUDT5, eliminates toxic nucleotide derivatives from the cell and regulate the levels of important signaling nucleotides and their metabolites. NUDT5 functions as a MutT-related protein and catalyzes the hydrolysis of 8-oxoGDP to 8-oxoGMP, thereby preventing misincorporation of 8-oxoGua into RNA. NUDT5 may play significant roles in regulating the G1-S transition in mammalian cells. It can also hydrolyze other nucleotide sugars with low activity.
| Product Name: | NUDT5 Recombinant Protein (RPES4610) |
| Product Code: | RPES4610 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | hYSAH1,YSA1,YSA1H,YSAH1 |
| Accession: | Q9UKK9 |
| Sequence: | Glu2-Phe219 |
| Fusion tag: | N-His |
| Endotoxin: | Please contact us for more information. |
| Protein Construction: | A DNA sequence encoding the human NUDT5 (Q9UKK9) (Glu2-Phe219) was expressed with a polyhistidine tag at the N-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 26.3 kDa |
| AP Mol Mass: | 35 kDa |
| Formulation: | Lyophilized from sterile 50mM Tris, 10% glycerol, pH 8.0 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |