NPPA Monoclonal Antibody
- SKU:
- CAB22075
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | NPPA Monoclonal Antibody |
| Product Code: | CAB22075 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC51463 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Rat heart |
| Cellular Location: | Secreted |
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NPPA (NP_006163.1). |
| Sequence: | MSSFS TTTVS FLLLL AFQLL GQTRA NPMYN AVSNA DLMDF KNLLD HLEEK MPLED EVVPP QVLSE PNEEA GAALS PLPEV PPWTG EVSPA QRDGG ALGRG |
| Synonyms: | ANF, ANP, CDD, CDP, PND, ATFB6, ATRST2, CDD-ANF |
| Calculated MW: | 16kDa |
| Observed MW: | 16kDa |
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