Cell Biology Antibodies 6

NPPA Rabbit Polyclonal Antibody (CAB1609)

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SKU:
CAB1609
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
ANF, ANP, CDD, CDP, PND, ATFB6, ATRST2, CDD-ANF, NPPA
Research Use:
Cell Biology
Frequently bought together:

Description

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NPPA Antibody (CAB1609)

The NPPA Antibody (CAB1609) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is raised in rabbits and has high reactivity with human samples, making it ideal for use in Western blot applications. By binding to the NPPA protein, this antibody enables the detection and analysis of NPPA in various cell types, particularly in studies related to cardiovascular disease and hypertension.Atrial natriuretic peptide is a hormone produced by the heart in response to stretching of the cardiac atria, and plays a crucial role in regulating blood pressure and fluid balance.

This antibody is validated for use in WB, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:NPPA Antibody
SKU:CAB1609
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:LTWQ EIMS ITEL QGLN APSE PSFE PQAP APYL GPPP PTTY CPCS IHPD SGFP LPPP PYEL PAST SHVP DPPY SYGN MAIP VSKP LSLS GLLS EPLQ DPLA LLDI GLPA GPPK PQED PESD SGLS LN
Tested Applications:WB ELISA IF-P
Recommended Dilution:
WB1:500 - 1:2000
IF-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:ANF, ANP, CDD, CDP, PND, ATFB6, ATRST2, CDD-ANF, NPPA
Positive Sample:Mouse heart
Cellular Localization:Secreted.
Calculated MW:16kDa
Observed MW:17kDa

The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1.

Purification MethodAffinity purification
Gene ID4878
RRIDAB_2763531
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from Mouse heart using NPPA Rabbit pAb (CAB1609) at 1:1000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10 s.
Product ImageImmunofluorescence analysis of paraffin-embedded mouse heart using NPPA Rabbit pAb (CAB1609) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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