MyD88 Polyclonal Antibody

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SKU:
CAB21499
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IF

Description

Product Name:MyD88 Polyclonal Antibody
Product Code:CAB21499
Reactivity:Human, Mouse, Rat
Applications:Western blotting, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse, Rat
Tested Applications:WB, IF/ICC, ELISA
Key Applications:Western blotting, Immunofluorescence
Recommended Dilution:WB 1:500-1:1000, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Positive Samples:Raji, THP-1
Cellular Location:Cytoplasm

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-140 of human MyD88 (NP_002459.2).
Sequence:GAGSA APVSS TSSLP LAALN MRVRR RLSLF LNVRT QVAAD WTALA EEMDF EYLEI RQLET QADPT GRLLD AWQGR PGASV GRLLE LLTKL GRDDV LLELG PSIEE DCQKY ILKQQ QEEAE K
Synonyms:WM1, IMD68, MYD88D
Calculated MW:33kDa
Observed MW:33kDa
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