mutT Antibody (PACO34714)
- SKU:
- PACO34714
- Product Type:
- Antibody
- Reactivity:
- Bacteria - Escherichia coli
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | mutT Antibody (PACO34714) |
| Antibody SKU: | PACO34714 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Escherichia coli |
| Immunogen: | Recombinant Escherichia coli 8-oxo-dGTP diphosphatase protein (1-129AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions. MutT specifically degrades 8-oxo-dGTP to the monophosphate. |
| Synonyms: | 8-oxo-dGTP diphosphatase (8-oxo-dGTPase) (EC 3.6.1.55) (7,8-dihydro-8-oxoguanine-triphosphatase) (Mutator protein MutT) (dGTP pyrophosphohydrolase), mutT |
| UniProt Protein Function: | Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions. MutT specifically degrades 8-oxo-dGTP to the monophosphate. |
| UniProt Protein Details: | |
| NCBI Summary: | Nudix hydrolase. [More information is available at EcoGene: EG10626]. dGTP pyrophosphohydrolase (MutT) can catalyze the hydrolysis of all eight canonical nucleotides, but it shows a marked preference for dGTP. [More information is available at EcoCyc: EG10626]. |
| UniProt Code: | P08337 |
| NCBI GenInfo Identifier: | 16128092 |
| NCBI Gene ID: | 944824 |
| NCBI Accession: | NP_414641.1 |
| UniProt Secondary Accession: | P08337 |
| UniProt Related Accession: | P08337 |
| Molecular Weight: | 14,927 Da |
| NCBI Full Name: | dGTP-preferring nucleoside triphosphate pyrophosphohydrolase |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | mutT |
| NCBI Official Synonym Symbols: | ECK0100; JW0097; nudA |
| NCBI Protein Information: | dGTP-preferring nucleoside triphosphate pyrophosphohydrolase |
| UniProt Protein Name: | 8-oxo-dGTP diphosphatase |
| UniProt Synonym Protein Names: | 7,8-dihydro-8-oxoguanine-triphosphatase; Mutator protein MutT; dGTP pyrophosphohydrolase |
| Protein Family: | MutT-like protein |
| UniProt Gene Name: | mutT |
| UniProt Entry Name: | MUTT_ECOLI |
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