mutL Antibody (PACO50454)
- SKU:
- PACO50454
- Product Type:
- Antibody
- Reactivity:
- Bacteria - Escherichia coli
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | mutL Antibody (PACO50454) |
| Antibody SKU: | PACO50454 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Escherichia coli |
| Immunogen: | Recombinant Escherichia coli DNA mismatch repair protein MutL protein (1-615AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in Recombinant protein. All lanes: mutL antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. predicted band size: 68 kDa. observed band size: 68 kDa.. |
| Background: | This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of the final effector complex. The ATPase activity of MutL is stimulated by DNA. |
| Synonyms: | DNA mismatch repair protein MutL, mutL |
| UniProt Protein Function: | This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of the final effector complex. The ATPase activity of MutL is stimulated by DNA. |
| UniProt Protein Details: | |
| NCBI Summary: | MutL DNA-binding is required for methyl-directed mismatch repair (Robertson, 2006). [More information is available at EcoGene: EG11281]. MutL is one of the components of the MutHLS complex. [More information is available at EcoCyc: EG11281]. |
| UniProt Code: | P23367 |
| NCBI GenInfo Identifier: | 16131992 |
| NCBI Gene ID: | 948691 |
| NCBI Accession: | NP_418591.1 |
| UniProt Secondary Accession: | P23367,Q2M6D5 |
| UniProt Related Accession: | P23367 |
| Molecular Weight: | 67,924 Da |
| NCBI Full Name: | methyl-directed mismatch repair protein |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | mutL |
| NCBI Official Synonym Symbols: | ECK4166; JW4128 |
| NCBI Protein Information: | methyl-directed mismatch repair protein |
| UniProt Protein Name: | DNA mismatch repair protein MutL |
| UniProt Synonym Protein Names: | |
| Protein Family: | DNA mismatch repair protein |
| UniProt Gene Name: | mutL |
| UniProt Entry Name: |
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