MTPN Polyclonal Antibody
- SKU:
- CAB10599
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | MTPN Polyclonal Antibody |
| Product Code: | CAB10599 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm, Nucleus, perinuclear region |
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human MTPN (NP_665807.1). |
| Sequence: | MCDKE FMWAL KNGDL DEVKD YVAKG EDVNR TLEGG RKPLH YAADC GQLEI LEFLL LKGAD INAPD KHHIT PLLSA VYEGH VSCVK LLLSK GADKT VKGPD GLTAF EATDN QAIKA LLQ |
| Synonyms: | V-1, GCDP |
| Calculated MW: | 13kDa |
| Observed MW: | Refer to figures |
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