Description
| Product Name: | MRP4/ABCC4 Monoclonal Antibody |
| Product Code: | CAB22601 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC52223 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, HeLa, HT-29, SW620, LNCaP, Mouse kidney, Rat kidney |
| Cellular Location: | Membrane, Multi-pass membrane protein |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1067-1325 of human MRP4/ABCC4. (NP_005836.2). |
| Sequence: | Email for sequence |
| Synonyms: | MRP4, MOATB, MOAT-B |
| Calculated MW: | 150kDa |
| Observed MW: | 140-200kDa |