MRP4/ABCC4 Monoclonal Antibody (CAB21171)
- SKU:
- CAB21171
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | MRP4/ABCC4 Monoclonal Antibody |
| Product Code: | CAB21171 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC52221 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, C2C12, Mouse thymus, Rat brain, Rat kidney |
| Cellular Location: | Membrane, Multi-pass membrane protein |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1067-1325 of human MRP4/ABCC4 (NP_005836.2). |
| Sequence: | SQEKV GIVGR TGAGK SSLIS ALFRL SEPEG KIWID KILTT EIGLH DLRKK MSIIP QEPVL FTGTM RKNLD PFNEH TDEEL WNALQ EVQLK ETIED LPGKM DTELA ESGSN FSVGQ RQLVC LARAI LRKNQ ILIID EATAN VDPRT DELIQ KKIRE KFAHC TVLTI AHRLN TIIDS DKIMV LDSGR LKEYD EPYVL LQNKE SLFYK MVQQL GKAEA AALTE TAKQV YFKRN YPHIG HTDHM VTNTS NGQPS TLTIF ETAL |
| Synonyms: | MRP4, MOATB, MOAT-B |
| Calculated MW: | 150kDa |
| Observed MW: | 140-200kDa |
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