Cardiovascular Recombinant Proteins
Mouse Tissue Factor/TF Recombinant Protein (RPES0538)
- SKU:
- RPES0538
Description
Mouse Tissue Factor/TF Recombinant Protein
Tissue?Factor, also known as thromboplastin and CD142,?belongs to the tissue factor family which conteins 294 amino acid (aa). Mouse TF consists of a signal peptide (residues 1-28) and the mature chain (residues 29-294). It is a single-pass type I membrane protein that expressed in the liver oscillates in a circadian manner. Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII. Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
| Product Name: | Mouse Tissue Factor/TF Recombinant Protein (RPES0538) |
| Product Code: | RPES0538 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | Tissue factor, TF, Coagulation factor III, |
| Accession: | P20352 |
| Sequence: | Ala29-Glu251 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse Tissue factor is produced by our Mammalian expression system and the target gene encoding Ala29-Glu251 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 26.2 kDa |
| AP Mol Mass: | 35-42 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM TrisHCl,150mM NaCl,0.05%Brij35,pH7.5. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Mouse |
Research Area: |
Cardiovascular |
Related Products
Rat Tissue factor/TF Recombinant Protein (His tag)
Mouse Tissue Factor/CD142 Recombinant Protein (RPES2348)
