Mouse TGFbeta1/TGFB1 Recombinant Protein (RPES3406)

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SKU:
RPES3406
Product Type:
Recombinant Protein
Species:
Mouse

Description

system_update_altDatasheet

Mouse TGFbeta1/TGFB1 Recombinant Protein

Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

Product Name:Mouse TGFbeta1/TGFB1 Recombinant Protein (RPES3406)
Product Code:RPES3406
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:TGF-beta-1, CED, DPD1, TGFB, TGF-b1, TGFB1, CEDLAP,latency-associated peptide, TGFbeta, TGF-beta 1 protein, transforming growth factor beta-1
Accession:P04202
Sequence: Ala279-Ser390
Activity:Measured by its ability to inhibit IL-4-dependent proliferation of TF?1 human erythroleukemic cells. The ED50 for this effect is 5-25 pg/ml.
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed.
Purity:> 95 % as determined by SDS-PAGE
Mol Mass:12.8 kDa
AP Mol Mass:14 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 50mM Glycine,150mM NaCl,pH 2.5.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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