Cell Biology Recombinant Proteins

Mouse PSGL/CD162 Recombinant Protein (RPES0724)

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SKU:
RPES0724
Product Type:
Recombinant Protein
Species:
Mouse
Research Area:
Cell Biology

Description

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Mouse PSGL/CD162 Recombinant Protein

P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.

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