Mouse PIGR Recombinant Protein (RPES3741)
- SKU:
- RPES3741
- Product Type:
- Recombinant Protein
- Species:
- Mouse
Description
Mouse PIGR Recombinant Protein
Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.
| Product Name: | Mouse PIGR Recombinant Protein (RPES3741) |
| Product Code: | RPES3741 |
| Size: | 50µg |
| Species: | Mouse |
| Expressed Host: | HEK293 Cells |
| Synonyms: | Pigr |
| Accession: | NP_035212.2 |
| Sequence: | Met 1-Lys 645 |
| Fusion tag: | C-His |
| Activity: | Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse PIGR at 5 µg/ml (100 ?l/well) can bind mouse IgM with a linear range of 0.156-10 µg/ml. |
| Endotoxin: | <1.0 EU per µg of the protein as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the extracellular domain (Met 1-Lys 645) of mouse PIGR (NP_035212.2) precursor was expressed with a C-terminal polyhistidine tag. |
| Purity: | > 97 % as determined by SDS-PAGE |
| Mol Mass: | 70.8 kDa |
| AP Mol Mass: | 90-100 kDa |
| Formulation: | Lyophilized from sterile PBS, pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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