Mouse MYL9 Recombinant Protein (RPPB4041)

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SKU:
RPPB4041
Product Type:
Recombinant Protein
Species:
Mouse
Uniprot:
Q9CQ19

Description

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Product Name:Mouse MYL9 Recombinant Protein
Product Code:RPPB4041
Size:20µg
Species:Mouse
Target:MYL9
Synonyms:Myosin regulatory light polypeptide 9, Myosin regulatory light chain 2, Myosin regulatory light chain 9, Myl9, Myrl2.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:MYL9 protein solution (0.5mg/ml) containing Phosphate buffered saline (pH7.4), 10% glycerol�and�1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMSSKRA KAKTTKKRPQ RATSNVFAMF DQSQIQEFKE AFNMIDQNRD GFIDKEDLHD MLASLGKNPT DEYLEGMMNE APGPINFTMF LTMFGEKLNG TDPEDVIRNA FACFDEEASG FIHEDHLREL LTTMGDRFTD EEVDEMYREA PIDKKGNFNY VEFTRILKHG AKDKDD

MYL9 is one of the numerous regulatory myosin light chains. Myosin which is a structural component of the muscle consists of 2 heavy chains and 4 light chains. MYL9 is a myosin light chain regulates muscle contraction by modulating the ATPase activity of myosin heads. MYL9 binds calcium and is activated by myosin light chain kinase. Regulatory myosin light chains regulate contraction in smooth muscle and non-muscle cells via phosphorylation by MLCK (myosin light chain kinase). Phosphorylation of regulatory myosin light chains is catalyzed by MLCK in the presence of calcium and calmodulin and it increases the actin-activated myosin ATPase activity, thus regulates the contractile activity.

MYL9 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 196 amino acids (1-172 a.a) and having a molecular mass of 22.4kDa.MYL9 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9CQ19
NCBI GenInfo Identifier:198278553
NCBI Gene ID:98932
NCBI Accession:NP_742116.1
UniProt Secondary Accession:Q9CQ19,Q3TW15, Q80X77
UniProt Related Accession:Q9CQ19
Molecular Weight:19,854 Da
NCBI Full Name:myosin regulatory light polypeptide 9
NCBI Synonym Full Names:myosin, light polypeptide 9, regulatory
NCBI Official Symbol:Myl9��
NCBI Official Synonym Symbols:MLC20; RLC-C; Mylc2c; AI327049��
NCBI Protein Information:myosin regulatory light polypeptide 9
UniProt Protein Name:Myosin regulatory light polypeptide 9
UniProt Synonym Protein Names:Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 9
Protein Family:Myosin regulatory light polypeptide
UniProt Gene Name:Myl9��
UniProt Entry Name:
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