Mouse MGL2/CD301b Recombinant Protein (RPES1142)

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SKU:
RPES1142
Product Type:
Recombinant Protein
Species:
Mouse

Description

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Mouse MGL2/CD301b Recombinant Protein

Macrophage galactose N-acetyl-galactosamine-specific lectin 2(Mgl2), also known as CD301b, is a 38 kDa member that belongs to the C-type lectin family. Two MGL proteins are encoded by separate genes in the mouse, but share 91% amino acid (aa) identity in the extracellular domain (ECD). Only one MGL occurs in human and rat and this MGL is structurally more similar to mouse MGL1 than MGL2. However, human MGL and mouse MGL2 both bind specifically to terminal GalNAc residues, in contrast with mouse MGL1 which binds Lewis X. GalNAc recognition is likely to be important in dendritic cell-mediated tolerance to self-gangliosides as well as recognition of tumor antigens and parasite glycoproteins.

Product Name:Mouse MGL2/CD301b Recombinant Protein (RPES1142)
Product Code:RPES1142
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:Mgl2,CD301b,Macrophage galactose N-acetyl-galactosamine-specific lectin 2,Macrophage Galactose-type C-lectin 2
Accession:Q8JZN1
Sequence:Ser72-Pro232
Fusion tag:N-His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse MGL2 is produced by our Mammalian expression system and the target gene encoding Ser72-Pro232 is expressed with a 6His tag at the N-terminus.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:30.9 kDa
AP Mol Mass:30-40 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS,pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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