Mouse MEK4/MAP2K4 Recombinant Protein (RPES0525)
- SKU:
- RPES0525
- Product Type:
- Recombinant Protein
- Species:
- Mouse
Description
Mouse MEK4/MAP2K4 Recombinant Protein
Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK and MAP2K4, is a protein which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K4 / JNKK1 is a protein kinase which is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. MAP2K4 / JNKK1 has been shown to activate MAPK8 / JNK1, MAPK9 / JNK2, and MAPK14 / p38, but not MAPK1 / ERK2 or MAPK3 / ERK1. MAP2K4 / JNKK1 is phosphorylated, and thus activated by MAP3K1 / MEKK. The stress-activated protein kinase (SAPK) pathways represent phosphorylation cascades that convey pro-apoptotic signals. The mitogen-activated protein kinase kinase (MAPKK) homolog MAP2K4 ( MKK4, SEK, JNKK1 ) is a centrally-placed mediator of the SAPK pathways.
| Product Name: | Mouse MEK4/MAP2K4 Recombinant Protein (RPES0525) |
| Product Code: | RPES0525 |
| Size: | 20µg |
| Species: | Mouse |
| Expressed Host: | Baculovirus-Insect Cells |
| Synonyms: | JNKK1,MEK4,MKK4,PRKMK4,Sek1,Serk1 |
| Accession: | P47809 |
| Sequence: | Ala 2-Asp 397 |
| Fusion tag: | N-His-GST |
| Endotoxin: | <1.0 EU per µg of the protein as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the mouse MAP2K4 (P47809) (Ala 2-Asp 397) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. |
| Purity: | > 90 % as determined by SDS-PAGE |
| Mol Mass: | 72 kDa |
| AP Mol Mass: | 65 kDa |
| Formulation: | Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.5 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Related Products
Mouse EGF Protein Recombinant Protein (RPPB0168)
Growth Factors & Cytokines Recombinant Proteins
Mouse MARCO Recombinant Protein (RPES1122)
Mouse ApoAI Recombinant Protein (RPES1371)
Metabolism Recombinant Proteins
Mouse S100A4 Recombinant Protein (RPES1856)
