Description
Antibody Name: | Mouse Ly-6G/Ly-6C (Gr-1) Monoclonal Antibody (APC Conjugated) |
Antibody Code: | AGEL1471 |
Size: | 200 Tests |
Clone: | RB6-8C5 |
Synonyms: | Gr-1,Gr1,Ly-6G/Ly-6C,Ly6G/Ly6C |
Host Species: | Rat |
Species Reactivity: | Mouse |
Applications: | FC |
Concentration: | 5uL |
Isotype: | IgG2a,k |
Conjugation: | APC |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
Gene ID: | 546644 ,17067 |
Uniprot: | P35461, P0CW02, P0CW03 |
Background: | Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity. |
C57BL/6 murine bone marrow cells are stained with Anti-Mouse Gr-1 Monoclonal Antibody(APC Conjugated)(filled gray histogram). Unstained bone marrow cells (empty black histogram) are used as control. |