Mouse/Human CD11b Monoclonal Antibody [M1/70](AGEL0304)

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SKU:
AGEL0304
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rat
Isotype:
IgG2b
Clone:
M1/70
Conjugation:
Unconjugated
Applications:
FC
Applications:
IP
Applications:
IHC

Description

system_update_altDatasheet
Antibody Name:Mouse/Human CD11b Monoclonal Antibody
Antibody Code:AGEL0304
Size:100µg
Clone:M1/70
Synonyms:Integrin alpha-M, Itgam, CD11 antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b
Host Species:Rat
Species Reactivity:Mouse, Human
Applications:FC, IP, IHC
Concentration:1mg/mL
Isotype:IgG2b
Conjugation:Unconjugated
Applications:FC, IP, IHC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:164093684
Uniprot:P05555, P11215
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
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