Growth Factors & Cytokines Recombinant Proteins

Mouse EGF Recombinant Protein (RPES0571)

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SKU:
RPES0571
Product Type:
Recombinant Protein
Species:
Mouse
Research Area:
Growth Factors & Cytokines

Description

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Mouse EGF Recombinant Protein

EGF is a single-pass type I membrane protein,containing 8 LDL-receptor class B repeats and 9 EGF-like domains. EGF results in cellular proliferation, differentiation, and survival.EGF is a low-molecular-weight polypeptide first purified from the mouse submandibular gland, but since then found in many human tissues including submandibular gland, parotid gland. Salivary EGF, which seems also regulated by dietary inorganic iodine, also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity. The biological effects of salivary EGF include healing of oral and gastroesophageal ulcers, inhibition of gastric acid secretion, stimulation of DNA synthesis as well as mucosal protection from intraluminal injurious factors such as gastric acid, bile acids, pepsin, and trypsin and to physical, chemical and bacterial agents.

Product Name:Mouse EGF Recombinant Protein (RPES0571)
Product Code:RPES0571
Size:10µg
Species:Mouse
Expressed Host:E.coli
Synonyms:Pro-epidermal growth factor, Epidermal growth factor,EGF
Accession:P01132
Sequence:Asn977-Arg1029
Fusion tag:C-6His
Activity:Measured in a cell proliferation assay using BALB/c 3T3 cells. The ED50 for this effect is 0.15-1.5 ng/ml.
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse epidermal growth factor is produced by our E.coli expression system and the target gene encoding Asn977-Arg1029 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by SDS-PAGE
Mol Mass:7.2 kDa
AP Mol Mass:10 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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