Chemokines Recombinant Proteins

Mouse CXCL2/MIP-2 Recombinant Protein (RPES0282)

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RPES0282

Description

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Mouse CXCL2/MIP-2 Recombinant Protein

C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.

Product Name:Mouse CXCL2/MIP-2 Recombinant Protein (RPES0282)
Product Code:RPES0282
Size:10µg
Species:Mouse
Expressed Host:E.coli
Synonyms:MIP-2, chemokine ligand 2, C-X-C motif chemokine 2, GRO beta, GRO2, GROB, Gro-beta, Growth-regulated protein beta, Macrophage Inflammatory Protein-2-alpha, melanoma growth stimulatory activity beta, cxcl2, MGSA-b, MGSA-beta, MIP2A, MIP2-alpha, SCYB2.
Accession:P10889
Sequence:Ala28-Asn100
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse C-X-C motif chemokine 2 is produced by our E.coli expression system and the target gene encoding Ala28-Asn100 is expressed.
Purity:> 95 % as determined by SDS-PAGE
Mol Mass:7.9 kDa
AP Mol Mass:10 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM Tris,150mM NaCl,pH8.0.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Additional Information

Product Type:
Recombinant Protein
Species:
Mouse
Research Area:
Chemokines
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