Chemokines Recombinant Proteins
Mouse CXCL2/MIP-2 Recombinant Protein (RPES0282)
- SKU:
- RPES0282
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Research Area:
- Chemokines
Description
Mouse CXCL2/MIP-2 Recombinant Protein
C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.
| Product Name: | Mouse CXCL2/MIP-2 Recombinant Protein (RPES0282) |
| Product Code: | RPES0282 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | E.coli |
| Synonyms: | MIP-2, chemokine ligand 2, C-X-C motif chemokine 2, GRO beta, GRO2, GROB, Gro-beta, Growth-regulated protein beta, Macrophage Inflammatory Protein-2-alpha, melanoma growth stimulatory activity beta, cxcl2, MGSA-b, MGSA-beta, MIP2A, MIP2-alpha, SCYB2. |
| Accession: | P10889 |
| Sequence: | Ala28-Asn100 |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse C-X-C motif chemokine 2 is produced by our E.coli expression system and the target gene encoding Ala28-Asn100 is expressed. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 7.9 kDa |
| AP Mol Mass: | 10 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM Tris,150mM NaCl,pH8.0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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