Mouse CREG/CREG1 Recombinant Protein (RPES0974)
- SKU:
- RPES0974
- Product Type:
- Recombinant Protein
- Species:
- Mouse
Description
system_update_altDatasheet
Mouse CREG/CREG1 Recombinant Protein
CREG1 belongs to the CREG family. It is a adenovirus E1A protein which both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. Thus it may contribute to the transcriptional control of cell growth and differentiation. The transcriptional control activity of cell growth requires interaction with IGF2R. CREG1 also antagonizes transcriptional activation and cellular transformation by E1A. It shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. CREG1 gene may contribute to the transcriptional control of cell growth and differentiation.
| Product Name: | Mouse CREG/CREG1 Recombinant Protein (RPES0974) |
| Product Code: | RPES0974 |
| Size: | 20µg |
| Species: | Mouse |
| Expressed Host: | HEK293 Cells |
| Synonyms: | CREG1, cellular repressor of E1A-stimulated genes, cellular repressor of E1A-stimulated genes 1CREG, protein CREG1 |
| Accession: | O88668 |
| Sequence: | Met1-Gln220 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg of the protein as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the mouse CREG (O88668)(Met1-Gln220) was expressed with the Fc region of human IgG1 at the C-terminus. |
| Purity: | > 90 % as determined by SDS-PAGE |
| Mol Mass: | 48.5 kDa |
| AP Mol Mass: | 59 kDa |
| Formulation: | Lyophilized from sterile PBS, pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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