Mouse CD40 Monoclonal Antibody [FGK4.5/FGK45](AGEL0140)

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SKU:
AGEL0140
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a
Clone:
FGK4.5/FGK45
Conjugation:
Unconjugated
Applications:
FC

Description

system_update_altDatasheet
Antibody Name:Mouse CD40 Monoclonal Antibody
Antibody Code:AGEL0140
Size:100µg
Clone:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5, Cd40, B-cell surface antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5
Host Species:Rat
Species Reactivity:Mouse
Concentration:1mg/mL
Isotype:IgG2a
Conjugation:Unconjugated
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:21939
Uniprot:P27512
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
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