Mouse CD27/TNFRSF7 Recombinant Protein (RPES4700)

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SKU:
RPES4700
Product Type:
Recombinant Protein
Species:
Mouse

Description

system_update_altDatasheet

Mouse CD27/TNFRSF7 Recombinant Protein

Mouse CD27 is a single-pass type I membrane protein which is a member of the tumor necrosis factor receptor superfamily. CD27 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-?B and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Product Name:Mouse CD27/TNFRSF7 Recombinant Protein (RPES4700)
Product Code:RPES4700
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:CD27 antigen, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7,S152,Tnfrsf7,Tp55
Accession:NP_001028298.1
Sequence:Pro24-Arg182
Fusion tag:C-Fc-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse CD27 antigen is produced by our Mammalian expression system and the target gene encoding Pro24-Arg182 is expressed with a Fc, 6His tag at the C-terminus.
Purity:> 95 % as determined by SDS-PAGE
Mol Mass:45.8 kDa
AP Mol Mass:60-66 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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