Description
system_update_altDatasheet
Antibody Name: | Mouse CD183 Monoclonal Antibody |
Antibody Code: | AGEL0428 |
Size: | 100µg |
Clone: | CXCR3-173 |
Synonyms: | C-X-C chemokine receptor type 3, Cxcr3, CXC-R3, CXCR-3, Interferon-inducible protein 10 receptor, IP-10 receptor, CD183 |
Host Species: | Hamster |
Species Reactivity: | Mouse |
Applications: | FC |
Concentration: | 1mg/mL |
Isotype: | IgG |
Conjugation: | Unconjugated |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | PBS with 0.05% Proclin300 |
Storage: | Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Gene ID: | 12766 |
Uniprot: | O88410 |
Background: | CD183, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes. |