Mouse CD183 Monoclonal Antibody (Biotin Conjugated) [CXCR3-173](AGEL0429)

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SKU:
AGEL0429
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
CXCR3-173
Conjugation:
Biotin
Applications:
FC

Description

system_update_altDatasheet
Antibody Name:Mouse CD183 Monoclonal Antibody (Biotin Conjugated)
Antibody Code:AGEL0429
Size:100µg
Clone:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3, Cxcr3, CXC-R3, CXCR-3, Interferon-inducible protein 10 receptor, IP-10 receptor, CD183
Host Species:Hamster
Species Reactivity:Mouse
Applications:FC
Concentration:1mg/mL
Isotype:IgG
Conjugation:Biotin
Applications:FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300, 1% BSA
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:12766
Uniprot:O88410
Background:CD183, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.
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