Mouse CD18 Monoclonal Antibody [M12/2](AGEL0426)

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SKU:
AGEL0426
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a
Clone:
M12/2
Conjugation:
Unconjugated
Applications:
FC
Applications:
WB
Applications:
IHC
Applications:
IP

Description

system_update_altDatasheet
Antibody Name:Mouse CD18 Monoclonal Antibody
Antibody Code:AGEL0426
Size:100µg
Clone:M12/2
Synonyms:Integrin beta-2, Itgb2, Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta, Complement receptor C3 subunit beta, CD18
Host Species:Rat
Species Reactivity:Mouse
Applications:FC, WB, IHC, IP
Concentration:1mg/mL
Isotype:IgG2a
Conjugation:Unconjugated
Applications:FC, WB, IHC, IP
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:16414
Uniprot:P11835
Background:CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is able to block tumor cell metastasis and enhance cell adhesion.
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