Mouse CD120b Monoclonal Antibody [TR75-54.7](AGEL0161)
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](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/11072/15126/mouse-cd120b-monoclonal-antibody-tr75-54.7agel0161__35114__12847.1706269341.jpg?c=1 "Mouse CD120b Monoclonal Antibody [TR75-54.7](AGEL0161)")
- SKU:
- AGEL0161
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Hamster
- Isotype:
- IgG
- Clone:
- TR75-54.7
- Conjugation:
- Unconjugated
- Applications:
- FC
- Applications:
- WB
- Applications:
- Block
- Applications:
- IP
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/11072/15126/mouse-cd120b-monoclonal-antibody-tr75-54.7agel0161__35114__12847.1706269341.jpg?c=1&imbypass=on "Mouse CD120b Monoclonal Antibody [TR75-54.7](AGEL0161)")
Description
system_update_altDatasheet
| Antibody Name: | Mouse CD120b Monoclonal Antibody |
| Antibody Code: | AGEL0161 |
| Size: | 100µg |
| Clone: | TR75-54.7 |
| Synonyms: | Tumor necrosis factor receptor superfamily member 1B, Tnfrsf1b, Tumor necrosis factor receptor 2, TNF-R2, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor, CD120b |
| Host Species: | Hamster |
| Species Reactivity: | Mouse |
| Applications: | FC, WB, Block, IP |
| Concentration: | 1mg/mL |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Applications: | FC, WB, Block, IP |
| Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Storage Buffer: | PBS with 0.05% Proclin300 |
| Storage: | Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Gene ID: | 21938 |
| Uniprot: | P25119 |
| Background: | CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state. |
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