Description
Antibody Name: | Mouse CD11c Monoclonal Antibody (AF647 Conjugated) |
Antibody Code: | AGEL0512 |
Size: | 50 Tests |
Clone: | N418 |
Synonyms: | Integrin alpha-X,Itgax,CD11 antigen-like family member C,Leukocyte adhesion receptor p150+95,CD11c |
Host Species: | Armenian Hamster |
Species Reactivity: | Mouse |
Applications: | FC |
Concentration: | 5uL |
Isotype: | IgG2a,k |
Conjugation: | AF647 |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
Gene ID: | 16411 |
Uniprot: | Q9QXH4 |
Background: | CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54. |
C57BL/6 murine splenocytes are stained with Anti-Mouse CD11c Monoclonal Antibody(AF647 Conjugated) and Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody(FITC Conjugated)(left). Splenocytes stained with Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody(FITC Conjugated)(right) are used as control. |