Mouse CD119 Monoclonal Antibody (APC Conjugated) [GR-20](AGEL1440)
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](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/12445/16497/mouse-cd119-monoclonal-antibody-apc-conjugated-gr-20agel1440__68450__24810.1706270023.jpg?c=1 "Mouse CD119 Monoclonal Antibody (APC Conjugated) [GR-20](AGEL1440)")
- SKU:
- AGEL1440
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FC
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- IgG2a,k
- Clone:
- GR-20
- Conjugation:
- APC
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/12445/16497/mouse-cd119-monoclonal-antibody-apc-conjugated-gr-20agel1440__68450__24810.1706270023.jpg?c=1&imbypass=on "Mouse CD119 Monoclonal Antibody (APC Conjugated) [GR-20](AGEL1440)")
Description
| Antibody Name: | Mouse CD119 Monoclonal Antibody (APC Conjugated) |
| Antibody Code: | AGEL1440 |
| Size: | 50µg |
| Clone: | GR-20 |
| Synonyms: | Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119 |
| Host Species: | Rat |
| Species Reactivity: | Mouse |
| Applications: | FC |
| Concentration: | 1mg/mL |
| Isotype: | IgG2a,k |
| Conjugation: | APC |
| Applications: | FC |
| Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
| Gene ID: | 15979 |
| Uniprot: | P15261 |
| Background: | CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses. |
 | C57BL/6 murine splenocytes are stained with Anti-Mouse CD119 Monoclonal Antibody(APC Conjugated)[Used at ?g/106 cells dilution](filled gray histogram). Unstained splenocytes (empty black histogram) are used as control. |
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