Description
Antibody Name: | Mouse CD106 Monoclonal Antibody (APC Conjugated) |
Antibody Code: | AGEL1174 |
Size: | 50µg |
Clone: | M/K-2.7 |
Synonyms: | Vascular cell adhesion protein 1,Vcam1,V-CAM 1,VCAM-1,CD106 |
Host Species: | Rat |
Species Reactivity: | Mouse |
Applications: | FC |
Concentration: | 1mg/mL |
Isotype: | IgG2a,k |
Conjugation: | APC |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
Gene ID: | 22329 |
Uniprot: | P29533 |
Background: | CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin). |
C57BL/6 murine bone marrow cells are stained with Anti-Mouse CD106 Monoclonal Antibody(APC Conjugated)[Used at ?g/106 cells dilution](filled gray histogram). Unstained bone marrow cells (empty black histogram) are used as control. |