Name: Mouse CD103 Monoclonal Antibody (PE/Cyanine5 Conjugated) [M290](AGEL1157)
SKU: AGEL1157
Availability: OutOfStock

Mouse CD103 Monoclonal Antibody (PE/Cyanine5 Conjugated) [M290](AGEL1157)

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SKU:

AGEL1157

Product Type:

Antibody

Antibody Type:

Monoclonal Antibody

Applications:

Reactivity:

Mouse

Host Species:

Rat

Isotype:

IgG2a,k

Clone:

M290

Conjugation:

PE/Cy5

Description

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OverviewAntibody Name:Mouse CD103 Monoclonal Antibody (PE/Cyanine5 Conjugated)Antibody Code:AGEL1148Size:50 TestsClone:M290

OverviewAntibody Name:Mouse CD103 Monoclonal Antibody (PE Conjugated)Antibody Code:AGEL1145Size:50 TestsClone:M290Syno

OverviewAntibody Name:Mouse CD103 Monoclonal Antibody (PE Conjugated)Antibody Code:AGEL1154Size:50µgClone:M290Sy

OverviewAntibody Name:Mouse CD103 Monoclonal Antibody (PE/Cyanine7 Conjugated)Antibody Code:AGEL1149Size:50 TestsClone:M290

OverviewAntibody Name:Mouse CD103 Monoclonal Antibody (PE/Cyanine7 Conjugated)Antibody Code:AGEL1158Size:50µgClone:M290<

Concentration:	1mg/mL
Isotype:	IgG2a,k
Conjugation:	PE/Cyanine5
Applications:	FC
Recommended Dilution:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:	PBS with 0.05% Proclin300, 1% BSA
Storage:	Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Gene ID:	16407
Uniprot:	Q60677
Background:	CD103 is a type I transmembrane glycoprotein known as αE integrin or Integrin αIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.