Description
Product Name: | MOB1A/B Monoclonal Antibody |
Product Code: | CAB23963 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC62859 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | K-562, Daudi, HuH-7(Low expression control), C6 |
Cellular Location: | Cytoplasm, nucleus |
The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MOB1A/B (NP_060691.2). |
Sequence: | MSFLF SSRSS KTFKP KKNIP EGSHQ YELLK HAEAT LGSGN LRQAV MLPEG EDLNE WIAVN TVDFF NQINM LYGTI TEFCT EASCP VMSAG PRYEY HWADG |
Synonyms: | MOB1, MATS1, Mob4B, C2orf6, MOBK1B, MABKL1B, MOBKL1B |
Calculated MW: | 25kDa |
Observed MW: | 25kDa |