MEK7 Polyclonal Antibody
- SKU:
- CAB23058
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | MEK7 Polyclonal Antibody |
| Product Code: | CAB23058 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:100-1:500, IF/ICC 1:20-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | Rat skeletal muscle |
| Cellular Location: | Cytoplasm, Nucleus |
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant protein of human MEK7. |
| Sequence: | DPPDP TKPDY DIRAD VWSLG ISLVE LATGQ FPYKN CKTDF EVLTK VLQEE PPLLP GHMGF SGDFQ SFVKD CLTKD HRKRP KYNKL LEHSF IKRYE TLEVD VASWF KDVMA KTESP RTSGV LSQPH LPFFR |
| Synonyms: | MEK, MKK7, JNKK2, MEK 7, MAPKK7, PRKMK7, SAPKK4, SAPKK-4 |
| Calculated MW: | 47kDa |
| Observed MW: | 47kDa |
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