Description
Product Name: | Meckelin Monoclonal Antibody |
Product Code: | CAB21162 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC3051 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | PC-12, 293T, U-87MG, T47D, Jurkat, mESCs, Mouse brain |
Cellular Location: | Cell membrane, Cytoplasm, Endoplasmic reticulum membrane, Multi-pass membrane protein, cilium basal body, cytoskeleton |
The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6).
Immunogen: | Recombinant protein of Human Meckelin. |
Sequence: | Email for sequence |
Synonyms: | MKS3, JBTS6, NPHP11, TNEM67, MECKELIN |
Calculated MW: | 112kDa |
Observed MW: | 112kDa |